Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms

Yes-associated protein (YAP) and its paralog WW domain containing transcription regulator 1 (TAZ) are important regulators of multiple cellular functions such as proliferation, differentiation, and survival. On the tissue level, YAP/TAZ are essential for embryonic development, organ size control and...

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Bibliographic Details
Published in:Clin Transl Med
Main Authors: Dobrokhotov, Oleg, Samsonov, Mikhail, Sokabe, Masahiro, Hirata, Hiroaki
Format: Artigo
Language:Inglês
Published: Springer Berlin Heidelberg 2018
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6087706/
https://ncbi.nlm.nih.gov/pubmed/30101371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40169-018-0202-9
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