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YAP and TAZ: a nexus for Hippo signaling and beyond

The Hippo pathway is a potent regulator of cellular proliferation, differentiation, and tissue homeostasis. Here we review the regulatory mechanisms of the Hippo pathway and discuss the function of Yes-associated protein (YAP)/transcriptional coactivator with a PDZ-binding domain (TAZ), the prime me...

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Détails bibliographiques
Publié dans:Trends Cell Biol
Auteurs principaux: Hansen, Carsten Gram, Moroishi, Toshiro, Guan, Kun-Liang
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4554827/
https://ncbi.nlm.nih.gov/pubmed/26045258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcb.2015.05.002
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