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The emerging roles of YAP and TAZ in cancer

Yes-associated protein (YAP) and transcriptional co-activator with PDZ-binding motif (TAZ) are the major downstream effectors of the Hippo pathway, which regulates tissue homeostasis, organ size, regeneration and tumorigenesis. In this Progress article, we summarize the current understanding of the...

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Publicat a:Nat Rev Cancer
Autors principals: Moroishi, Toshiro, Hansen, Carsten Gram, Guan, Kun-Liang
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4562315/
https://ncbi.nlm.nih.gov/pubmed/25592648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc3876
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