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The emerging roles of YAP and TAZ in cancer

Yes-associated protein (YAP) and transcriptional co-activator with PDZ-binding motif (TAZ) are the major downstream effectors of the Hippo pathway, which regulates tissue homeostasis, organ size, regeneration and tumorigenesis. In this Progress article, we summarize the current understanding of the...

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Pubblicato in:Nat Rev Cancer
Autori principali: Moroishi, Toshiro, Hansen, Carsten Gram, Guan, Kun-Liang
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4562315/
https://ncbi.nlm.nih.gov/pubmed/25592648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc3876
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