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The emerging roles of YAP and TAZ in cancer

Yes-associated protein (YAP) and transcriptional co-activator with PDZ-binding motif (TAZ) are the major downstream effectors of the Hippo pathway, which regulates tissue homeostasis, organ size, regeneration and tumorigenesis. In this Progress article, we summarize the current understanding of the...

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Detalhes bibliográficos
Publicado no:Nat Rev Cancer
Main Authors: Moroishi, Toshiro, Hansen, Carsten Gram, Guan, Kun-Liang
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4562315/
https://ncbi.nlm.nih.gov/pubmed/25592648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc3876
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