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Characterization of Hippo pathway components by gene inactivation

The Hippo pathway is important for regulating tissue homeostasis and its dysregulation has been implicated in human cancer. However, it is not well understood how the Hippo pathway becomes dysregulated because few mutations in core Hippo pathway components have been identified. Therefore, much work...

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Detalhes bibliográficos
Publicado no:Mol Cell
Main Authors: Plouffe, Steven W., Meng, Zhipeng, Lin, Kimberly C., Lin, Brian, Hong, Audrey W., Chun, Justin V., Guan, Kun-Liang
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5137798/
https://ncbi.nlm.nih.gov/pubmed/27912098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.10.034
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