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Critical roles of phosphoinositides and NF2 in Hippo pathway regulation
The Hippo pathway is a master regulator of tissue homeostasis and organ size. NF2 is a well-established tumor suppressor, and loss of NF2 severely compromises Hippo pathway activity. However, the precise mechanism of how NF2 mediates upstream signals to regulate the Hippo pathway is not clear. Here...
Gespeichert in:
| Veröffentlicht in: | Genes Dev |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Cold Spring Harbor Laboratory Press
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7111263/ https://ncbi.nlm.nih.gov/pubmed/32115406 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.333435.119 |
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