Binding of Antiphospholipid Antibodies to Discontinuous Epitopes on Domain I of Human β(2)-Glycoprotein I: Mutation Studies Including Residues R39 to R43

gan Ioannou, Yiannis, Pericleous, Charis, Giles, Ian, Latchman, David S., Isenberg, David A., Rahman, Anisur
Cyhoeddwyd 2007

Autoimmune rheumatic disease IgG has differential effects upon neutrophil integrin activation that is modulated by the endothelium

gan Khawaja, Akif A., Pericleous, Charis, Ripoll, Vera M., Porter, Joanna C., Giles, Ian P.
Cyhoeddwyd yn Sci Rep (2019)

Antibodies to domain I of β-2-glycoprotein I and IgA antiphospholipid antibodies in patients with ‘seronegative’ antiphospholipid syndrome

gan Cousins, Laura, Pericleous, Charis, Khamashta, Munther, Bertolaccini, Maria Laura, Ioannou, Yiannis, Giles, Ian, Rahman, Anisur
Cyhoeddwyd yn Ann Rheum Dis (2015)

Development of a high yield expression and purification system for Domain I of Beta-2-glycoprotein I for the treatment of APS

gan McDonnell, Thomas, Pericleous, Charis, Laurine, Emmanuelle, Tommasi, Rita, Garza-Garcia, Acely, Giles, Ian, Ioannou, Yiannis, Rahman, Anisur
Cyhoeddwyd yn BMC Biotechnol (2015)

Serum nitrated nucleosome levels in patients with systemic lupus erythematosus: a retrospective longitudinal cohort study

gan Croca, Sara, Bassett, Paul, Pericleous, Charis, Alber, Karim Fouad, Latchman, David, Isenberg, David, Giles, Ian, Rahman, Anisur, Ioannou, Yiannis
Cyhoeddwyd 2014

Purified IgG from Patients with Obstetric but not IgG from Non-obstetric Antiphospholipid Syndrome Inhibit Trophoblast Invasion

gan Poulton, Katie, Ripoll, Vera M, Pericleous, Charis, Meroni, Pier Luigi, Gerosa, Maria, Ioannou, Yiannis, Rahman, Anisur, Giles, Ian P
Cyhoeddwyd yn Am J Reprod Immunol (2015)

Antiphospholipid antibody levels in early systemic lupus erythematosus: are they associated with subsequent mortality and vascular events?

gan Pericleous, Charis, D’Souza, Amrita, McDonnell, Thomas, Ripoll, Vera M, Leach, Oliver, Isenberg, David, Giles, Ian, Rahman, Anisur
Cyhoeddwyd yn Rheumatology (Oxford) (2020)

The role of beta-2-glycoprotein I in health and disease associating structure with function: More than just APS

gan McDonnell, Thomas, Wincup, Chris, Buchholz, Ina, Pericleous, Charis, Giles, Ian, Ripoll, Vera, Cohen, Hannah, Delcea, Mihaela, Rahman, Anisur
Cyhoeddwyd yn Blood Rev (2020)

Anti-factor Xa antibodies in patients with antiphospholipid syndrome and their effects upon coagulation assays

gan Artim-Esen, Bahar, Pericleous, Charis, Mackie, Ian, Ripoll, Vera M, Latchman, David, Isenberg, David, Rahman, Anisur, Ioannou, Yiannis, Giles, Ian
Cyhoeddwyd yn Arthritis Res Ther (2015)

Antiphospholipid Antibodies to Domain I of Beta-2-Glycoprotein I Show Different Subclass Predominance in Comparison to Antibodies to Whole Beta-2-glycoprotein I

gan McDonnell, Thomas, Artim-Esen, Bahar, Wincup, Chris, Ripoll, Vera M., Isenberg, David, Giles, Ian P., Rahman, Anisur, Pericleous, Charis
Cyhoeddwyd yn Front Immunol (2018)

Antiphospholipid antibodies enhance rat neonatal cardiomyocyte apoptosis in an in vitro hypoxia/reoxygenation injury model via p38 MAPK

gan Bourke, Lauren T, McDonnell, Thomas, McCormick, James, Pericleous, Charis, Ripoll, Vera M, Giles, Ian, Rahman, Anisur, Stephanou, Anastasis, Ioannou, Yiannis
Cyhoeddwyd yn Cell Death Dis (2017)

Oxidation of β2-glycoprotein I associates with IgG antibodies to domain I in patients with antiphospholipid syndrome

gan Raimondo, Maria Gabriella, Pericleous, Charis, Radziszewska, Anna, Borghi, Maria Orietta, Pierangeli, Silvia, Meroni, Pier Luigi, Giles, Ian, Rahman, Anisur, Ioannou, Yiannis
Cyhoeddwyd yn PLoS One (2017)

Hydroxychloroquine Protects against Cardiac Ischaemia/Reperfusion Injury In Vivo via Enhancement of ERK1/2 Phosphorylation

gan Bourke, Lauren, McCormick, James, Taylor, Valerie, Pericleous, Charis, Blanchet, Benoit, Costedoat-Chalumeau, Nathalie, Stuckey, Daniel, Lythgoe, Mark F., Stephanou, Anastasis, Ioannou, Yiannis
Cyhoeddwyd yn PLoS One (2015)

Evaluating the conformation of recombinant domain I of β(2)-glycoprotein I and its interaction with human monoclonal antibodies

gan Pericleous, Charis, Miles, Jennifer, Esposito, Diego, Garza-Garcia, Acely, Driscoll, Paul C., Lambrianides, Anastasia, Latchman, David, Isenberg, David, Rahman, Anisur, Ioannou, Yiannis, Giles, Ian
Cyhoeddwyd 2011

Effects of polyclonal IgG derived from patients with different clinical types of the antiphospholipid syndrome on monocyte signalling pathways

gan Lambrianides, Anastasia, Carroll, Christopher J., Pierangeli, Silvia S., Pericleous, Charis, Branch, Ware, Rice, Jurhee, Latchman, David S., Townsend, Paul, Isenberg, David A., Rahman, Anisur, Giles, Ian P.
Cyhoeddwyd 2010

Antiphospholipid antibodies induce a pro-inflammatory response in first trimester trophoblast via the TLR4/MyD88 pathway

gan Mulla, Melissa J., Brosens, Jan J., Chamley, Larry W., Giles, Ian, Pericleous, Charis, Rahman, Anisur, Joyce, Shawna K., Panda, Britta, Paidas, Michael J., Abrahams, Vikki M.
Cyhoeddwyd 2009

Gene expression profiling identifies distinct molecular signatures in thrombotic and obstetric antiphospholipid syndrome

gan Ripoll, Vera M., Pregnolato, Francesca, Mazza, Simona, Bodio, Caterina, Grossi, Claudia, McDonnell, Thomas, Pericleous, Charis, Meroni, Pier Luigi, Isenberg, David A., Rahman, Anisur, Giles, Ian P.
Cyhoeddwyd yn J Autoimmun (2018)

Factor Xa Mediates Calcium Flux in Endothelial Cells and is Potentiated by Igg From Patients With Lupus and/or Antiphospholipid Syndrome

gan Artim-Esen, Bahar, Smoktunowicz, Natalia, McDonnell, Thomas, Ripoll, Vera M., Pericleous, Charis, Mackie, Ian, Robinson, Eifion, Isenberg, David, Rahman, Anisur, Ioannou, Yiannis, Chambers, Rachel C., Giles, Ian
Cyhoeddwyd yn Sci Rep (2017)

Interactions of human monoclonal and polyclonal antiphospholipid antibodies with serine proteases involved in hemostasis

gan Lambrianides, Anastasia, Turner-Stokes, Tabitha, Pericleous, Charis, Ehsanullah, Jasmine, Papadimitraki, Eva, Poulton, Katie, Ioannou, Yiannis, Lawrie, Andrew, Mackie, Ian, Chen, Pojen, Latchman, David, Isenberg, David, Rahman, Anisur, Giles, Ian
Cyhoeddwyd 2011

Measuring IgA Anti-β2-Glycoprotein I and IgG/IgA Anti-Domain I Antibodies Adds Value to Current Serological Assays for the Antiphospholipid Syndrome

gan Pericleous, Charis, Ferreira, Isabel, Borghi, Orietta, Pregnolato, Francesca, McDonnell, Thomas, Garza-Garcia, Acely, Driscoll, Paul, Pierangeli, Silvia, Isenberg, David, Ioannou, Yiannis, Giles, Ian, Meroni, Pier Luigi, Rahman, Anisur
Cyhoeddwyd yn PLoS One (2016)