Antiphospholipid Antibodies to Domain I of Beta-2-Glycoprotein I Show Different Subclass Predominance in Comparison to Antibodies to Whole Beta-2-glycoprotein I

Antiphospholipid antibodies (aPL), the serological hallmark of antiphospholipid syndrome (APS), are a heterogeneous group of autoantibodies raised against circulating blood proteins. Of these proteins, the phospholipid-binding b2-glycoprotein I (β2GPI) is considered to be the main autoantigen in APS...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: McDonnell, Thomas, Artim-Esen, Bahar, Wincup, Chris, Ripoll, Vera M., Isenberg, David, Giles, Ian P., Rahman, Anisur, Pericleous, Charis
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6173128/
https://ncbi.nlm.nih.gov/pubmed/30323817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02244
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