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The role of beta-2-glycoprotein I in health and disease associating structure with function: More than just APS

Beta-2-Glycoprotein I (β2GPI) plays a number of essential roles throughout the body. β2GPI, C-reactive protein and thrombomodulin are the only three proteins that possess the dual capability to up and down regulate the complement and coagulation systems depending upon external stimulus. Clinically,...

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Detalhes bibliográficos
Publicado no:Blood Rev
Main Authors: McDonnell, Thomas, Wincup, Chris, Buchholz, Ina, Pericleous, Charis, Giles, Ian, Ripoll, Vera, Cohen, Hannah, Delcea, Mihaela, Rahman, Anisur
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7014586/
https://ncbi.nlm.nih.gov/pubmed/31471128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.blre.2019.100610
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