Hydroxychloroquine Protects against Cardiac Ischaemia/Reperfusion Injury In Vivo via Enhancement of ERK1/2 Phosphorylation

An increasing number of investigations including human studies demonstrate that pharmacological ischaemic preconditioning is a viable way to protect the heart from myocardial ischaemia/reperfusion (I/R) injury. This study investigated the role of hydroxychloroquine (HCQ) in the heart during I/R inju...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Bourke, Lauren, McCormick, James, Taylor, Valerie, Pericleous, Charis, Blanchet, Benoit, Costedoat-Chalumeau, Nathalie, Stuckey, Daniel, Lythgoe, Mark F., Stephanou, Anastasis, Ioannou, Yiannis
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4670100/
https://ncbi.nlm.nih.gov/pubmed/26636577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0143771
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