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Development and validation of a clinical HPLC method for the quantification of hydroxychloroquine and its metabolites in whole blood
BACKGROUND: Therapeutic drug monitoring for hydroxychloroquine (HCQ) has been suggested to assess nonadherence and optimize treatment efficacy in systemic lupus erythematosus patients. MATERIALS & METHODS: After protein precipitation, HCQ and its metabolites, desethylhydroxychloroquine and deset...
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| 出版年: | Future Sci OA |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Future Science Ltd
2015
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5137978/ https://ncbi.nlm.nih.gov/pubmed/28031899 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fso.15.24 |
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