Alpha ketoglutarate levels, regulated by p53 and OGDH, determine autophagy and cell fate/apoptosis in response to Nutlin-3a

gan Duan, Lei, Perez, Ricardo E., Maki, Carl G.
Cyhoeddwyd yn Cancer Biol Ther (2018)

Two 4N Cell-Cycle Arrests Contribute to Cisplatin-Resistance

gan Shen, Hong, Perez, Ricardo E., Davaadelger, Batzaya, Maki, Carl G.
Cyhoeddwyd 2013

DZNep represses Bcl-2 expression and modulates apoptosis sensitivity in response to Nutlin-3a

gan Zhou, Yalu, Perez, Ricardo E., Duan, Lei, Maki, Carl G.
Cyhoeddwyd yn Cancer Biol Ther (2018)

Type I Interferon (IFN)-Regulated Activation of Canonical and Non-Canonical Signaling Pathways

gan Mazewski, Candice, Perez, Ricardo E., Fish, Eleanor N., Platanias, Leonidas C.
Cyhoeddwyd yn Front Immunol (2020)

Increasing cisplatin sensitivity by schedule-dependent inhibition of AKT and Chk1

gan Duan, Lei, Perez, Ricardo E, Hansen, Michael, Gitelis, Steven, Maki, Carl G
Cyhoeddwyd yn Cancer Biol Ther (2014)

Crosstalk between the IGF-1R/AKT/mTORC1 pathway and the tumor suppressors p53 and p27 determines cisplatin sensitivity and limits the effectiveness of an IGF-1R pathway inhibitor

gan Davaadelger, Batzaya, Duan, Lei, Perez, Ricardo E., Gitelis, Steven, Maki, Carl G.
Cyhoeddwyd yn Oncotarget (2016)

The histone demethylase JMJD2B is critical for p53-mediated autophagy and survival in Nutlin-treated cancer cells

gan Duan, Lei, Perez, Ricardo E., Lai, Xin, Chen, Ling, Maki, Carl G.
Cyhoeddwyd yn J Biol Chem (2019)

p53 promotes AKT and SP1-dependent metabolism through the pentose phosphate pathway that inhibits apoptosis in response to Nutlin-3a

gan Duan, Lei, Perez, Ricardo E, Chen, Ling, Blatter, Lothar A, Maki, Carl G
Cyhoeddwyd yn J Mol Cell Biol (2018)

The IGF-1R/AKT pathway has opposing effects on Nutlin-3a-induced apoptosis

gan Davaadelger, Batzaya, Perez, Ricardo E., Zhou, Yalu, Duan, Lei, Gitelis, Steven, Maki, Carl G.
Cyhoeddwyd yn Cancer Biol Ther (2017)

Prolyl endopeptidase inhibitor Y-29794 blocks the IRS1-AKT-mTORC1 pathway and inhibits survival and in vivo tumor growth of triple-negative breast cancer

gan Perez, Ricardo E, Calhoun, Sarah, Shim, Daeun, Levenson, Victor V., Duan, Lei, Maki, Carl G.
Cyhoeddwyd yn Cancer Biol Ther (2020)

p53-regulated autophagy is controlled by glycolysis and determines cell fate

gan Duan, Lei, Perez, Ricardo E., Davaadelger, Batzaya, Dedkova, Elena N., Blatter, Lothar A., Maki, Carl G.
Cyhoeddwyd yn Oncotarget (2015)

TRIP-1 via AKT modulation drives lung fibroblast/myofibroblast trans-differentiation

gan Nyp, Michael F, Navarro, Angels, Rezaiekhaligh, Mohammad H, Perez, Ricardo E, Mabry, Sherry M, Ekekezie, Ikechukwu I
Cyhoeddwyd 2014

Modeling the Etiology of p53-mutated Cancer Cells

gan Perez, Ricardo E., Shen, Hong, Duan, Lei, Kim, Reuben H., Kim, Terresa, Park, No-Hee, Maki, Carl G.
Cyhoeddwyd yn J Biol Chem (2016)

The Prolyl Peptidases PRCP/PREP Regulate IRS-1 Stability Critical for Rapamycin-induced Feedback Activation of PI3K and AKT

gan Duan, Lei, Ying, Guoguang, Danzer, Brian, Perez, Ricardo E., Shariat-Madar, Zia, Levenson, Victor V., Maki, Carl G.
Cyhoeddwyd 2014

Lung epithelial‐specific TRIP‐1 overexpression maintains epithelial integrity during hyperoxia exposure

gan Nyp, Michael F., Mabry, Sherry M., Navarro, Angels, Menden, Heather, Perez, Ricardo E., Sampath, Venkatesh, Ekekezie, Ikechukwu I.
Cyhoeddwyd yn Physiol Rep (2018)

Combined PI3Kα-mTOR Targeting of Glioma Stem Cells

gan Eckerdt, Frank D., Bell, Jonathan B., Gonzalez, Christopher, Oh, Michael S., Perez, Ricardo E., Mazewski, Candice, Fischietti, Mariafausta, Goldman, Stewart, Nakano, Ichiro, Platanias, Leonidas C.
Cyhoeddwyd yn Sci Rep (2020)

Restoration of DNA-Binding and Growth-Suppressive Activity of Mutant Forms of p53 Via a PCAF-Mediated Acetylation Pathway

gan PEREZ, RICARDO E., KNIGHTS, CHAD D., SAHU, GEETARAM, CATANIA, JASON, KOLUKULA, VAMSI K., STOLER, DANIEL, GRAESSMANN, ADOLF, OGRYZKO, VASILY, PISHVAIAN, MICHAEL, ALBANESE, CHRISTOPHER, AVANTAGGIATI, MARIA LAURA
Cyhoeddwyd 2010

Schlafen 5 as a Novel Therapeutic Target in Pancreatic Ductal Adenocarcinoma

gan Fischietti, Mariafausta, Eckerdt, Frank, Blyth, Gavin T., Arslan, Ahmet D., Mati, William M., Oku, Chidera V., Perez, Ricardo E., Lee-Chang, Catalina, Kosciuczuk, Ewa M., Saleiro, Diana, Beauchamp, Elspeth M., Lesniak, Maciej S., Verzella, Daniela, Sun, Leyu, Fish, Eleanor N., Yang, Guang-Yu, Qiang, Wenan, Platanias, Leonidas C.
Cyhoeddwyd yn Oncogene (2021)