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Increasing cisplatin sensitivity by schedule-dependent inhibition of AKT and Chk1
The effectiveness of DNA damaging chemotherapy drugs can be limited by activation of survival signaling pathways and cell cycle checkpoints that allow DNA repair. Targeting survival pathways and inhibiting cell cycle checkpoints may increase chemotherapy-induced cancer cell killing. AKT and Chk1 are...
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| Vydáno v: | Cancer Biol Ther |
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| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Taylor & Francis
2014
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4623033/ https://ncbi.nlm.nih.gov/pubmed/25482935 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15384047.2014.961876 |
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