Increasing cisplatin sensitivity by schedule-dependent inhibition of AKT and Chk1

Lignende værker

• Crosstalk between the IGF-1R/AKT/mTORC1 pathway and the tumor suppressors p53 and p27 determines cisplatin sensitivity and limits the effectiveness of an IGF-1R pathway inhibitor
  af: Davaadelger, Batzaya, et al.
  Udgivet: (2016)
• The IGF-1R/AKT pathway has opposing effects on Nutlin-3a-induced apoptosis
  af: Davaadelger, Batzaya, et al.
  Udgivet: (2017)
• p53 promotes AKT and SP1-dependent metabolism through the pentose phosphate pathway that inhibits apoptosis in response to Nutlin-3a
  af: Duan, Lei, et al.
  Udgivet: (2018)
• DZNep represses Bcl-2 expression and modulates apoptosis sensitivity in response to Nutlin-3a
  af: Zhou, Yalu, et al.
  Udgivet: (2018)
• Prolyl endopeptidase inhibitor Y-29794 blocks the IRS1-AKT-mTORC1 pathway and inhibits survival and in vivo tumor growth of triple-negative breast cancer
  af: Perez, Ricardo E, et al.
  Udgivet: (2020)