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DZNep represses Bcl-2 expression and modulates apoptosis sensitivity in response to Nutlin-3a
MDM2 antagonists stabilize and activate wild-type p53, and histone methyltransferase (HMT) inhibitors reduce methylation on histone lysines and arginines. Both MDM2 antagonists and HMT inhibitors are being developed as cancer therapeutics. Wild-type p53 expressing HCT116 colon cancer cells were resi...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Cancer Biol Ther |
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| Κύριοι συγγραφείς: | , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Taylor & Francis
2018
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5927691/ https://ncbi.nlm.nih.gov/pubmed/29394130 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2018.1433500 |
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