Combined PI3Kα-mTOR Targeting of Glioma Stem Cells

Glioblastoma (GBM) is the most common and lethal primary intrinsic tumour of the adult brain and evidence indicates disease progression is driven by glioma stem cells (GSCs). Extensive advances in the molecular characterization of GBM allowed classification into proneural, mesenchymal and classical...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Eckerdt, Frank D., Bell, Jonathan B., Gonzalez, Christopher, Oh, Michael S., Perez, Ricardo E., Mazewski, Candice, Fischietti, Mariafausta, Goldman, Stewart, Nakano, Ichiro, Platanias, Leonidas C.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7736588/
https://ncbi.nlm.nih.gov/pubmed/33318517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-78788-z
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