Combined PI3Kα-mTOR Targeting of Glioma Stem Cells

Glioblastoma (GBM) is the most common and lethal primary intrinsic tumour of the adult brain and evidence indicates disease progression is driven by glioma stem cells (GSCs). Extensive advances in the molecular characterization of GBM allowed classification into proneural, mesenchymal and classical...

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Publicat a:Sci Rep
Autors principals: Eckerdt, Frank D., Bell, Jonathan B., Gonzalez, Christopher, Oh, Michael S., Perez, Ricardo E., Mazewski, Candice, Fischietti, Mariafausta, Goldman, Stewart, Nakano, Ichiro, Platanias, Leonidas C.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7736588/
https://ncbi.nlm.nih.gov/pubmed/33318517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-78788-z
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