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Combined PI3Kα-mTOR Targeting of Glioma Stem Cells

Glioblastoma (GBM) is the most common and lethal primary intrinsic tumour of the adult brain and evidence indicates disease progression is driven by glioma stem cells (GSCs). Extensive advances in the molecular characterization of GBM allowed classification into proneural, mesenchymal and classical...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Eckerdt, Frank D., Bell, Jonathan B., Gonzalez, Christopher, Oh, Michael S., Perez, Ricardo E., Mazewski, Candice, Fischietti, Mariafausta, Goldman, Stewart, Nakano, Ichiro, Platanias, Leonidas C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7736588/
https://ncbi.nlm.nih.gov/pubmed/33318517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-78788-z
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