Survival analysis: coping with non proportional hazards in randomized trials

per Royston, Patrick, Parmar, Mahesh KB
Publicat 2011

Restricted mean survival time: an alternative to the hazard ratio for the design and analysis of randomized trials with a time-to-event outcome

per Royston, Patrick, Parmar, Mahesh KB
Publicat 2013

An approach to trial design and analysis in the era of non-proportional hazards of the treatment effect

per Royston, Patrick, Parmar, Mahesh KB
Publicat 2014

The need for a cultural shift from two-arm to multi-arm RCTS

per Sydes, Matthew R, Parmar, Mahesh KB
Publicat 2013

Augmenting the logrank test in the design of clinical trials in which non-proportional hazards of the treatment effect may be anticipated

per Royston, Patrick, Parmar, Mahesh K.B.
Publicat a BMC Med Res Methodol (2016)

A new measure of predictive ability for survival models

per Choodari-Oskooei, Babak, Royston, Patrick, Parmar, Mahesh KB
Publicat 2011

Discrimination-based sample size calculations for multivariable prognostic models for time-to-event data

per Jinks, Rachel C., Royston, Patrick, Parmar, Mahesh KB
Publicat a BMC Med Res Methodol (2015)

Assessing the impact of efficacy stopping rules on the error rates under the multi-arm multi-stage framework

per Blenkinsop, Alexandra, Parmar, Mahesh KB, Choodari-Oskooei, Babak
Publicat a Clin Trials (2019)

A multi-arm multi-stage clinical trial design for binary outcomes with application to tuberculosis

per Bratton, Daniel J, Phillips, Patrick PJ, Parmar, Mahesh KB
Publicat 2013

The extension of total gain (TG) statistic in survival models: properties and applications

per Choodari-Oskooei, Babak, Royston, Patrick, Parmar, Mahesh K.B.
Publicat a BMC Med Res Methodol (2015)

Impact of lack-of-benefit stopping rules on treatment effect estimates of two-arm multi-stage (TAMS) trials with time to event outcome

per Choodari-Oskooei, Babak, Parmar, Mahesh KB, Royston, Patrick, Bowden, Jack
Publicat 2013

Is It Possible to Conduct a Multi-Arm Multi-Stage Platform Trial in Parkinson’s Disease: Lessons Learned from Other Neurodegenerative Disorders and Cancer

per Zeissler, Marie-Louise, Li, Vivien, Parmar, Mahesh K.B., Carroll, Camille Buchholz
Publicat a J Parkinsons Dis (2020)

Designs for clinical trials with time-to-event outcomes based on stopping guidelines for lack of benefit

per Royston, Patrick, Barthel, Friederike M-S, Parmar, Mahesh KB, Choodari-Oskooei, Babak, Isham, Valerie
Publicat 2011

The DURATIONS randomised trial design: Estimation targets, analysis methods and operating characteristics

per Quartagno, Matteo, Carpenter, James R, Walker, A Sarah, Clements, Michelle, Parmar, Mahesh KB
Publicat a Clin Trials (2020)

Adjuvant therapy with oral sodium clodronate in locally advanced and metastatic prostate cancer: long-term overall survival results from the MRC PR04 and PR05 randomised controlled...

per Dearnaley, David P, Mason, Malcolm D, Parmar, Mahesh KB, Sanders, Karen, Sydes, Matthew R
Publicat 2009

Rethinking non-inferiority: a practical trial design for optimising treatment duration

per Quartagno, Matteo, Walker, A Sarah, Carpenter, James R, Phillips, Patrick PJ, Parmar, Mahesh KB
Publicat a Clin Trials (2018)

When should factorial designs be used for late-phase randomised controlled trials?

per White, Ian R, Szubert, Alexander J, Choodari-Oskooei, Babak, Walker, A Sarah, Parmar, Mahesh KB
Publicat a Clin Trials (2023)

Sharing data from clinical trials: the rationale for a controlled access approach

per Sydes, Matthew R, Johnson, Anthony L, Meredith, Sarah K, Rauchenberger, Mary, South, Annabelle, Parmar, Mahesh KB
Publicat a Trials (2015)

Adding new experimental arms to randomised clinical trials: Impact on error rates

per Choodari-Oskooei, Babak, Bratton, Daniel J, Gannon, Melissa R, Meade, Angela M, Sydes, Matthew R, Parmar, Mahesh KB
Publicat a Clin Trials (2020)

Postoperative radiotherapy for non‐small cell lung cancer

per Burdett, Sarah, Rydzewska, Larysa, Tierney, Jayne, Fisher, David, Parmar, Mahesh KB, Arriagada, Rodrigo, Pignon, Jean Pierre, Le Pechoux, Cecile
Publicat a Cochrane Database Syst Rev (2016)