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A multi-arm multi-stage clinical trial design for binary outcomes with application to tuberculosis
BACKGROUND: Randomised controlled trials are becoming increasingly costly and time-consuming. In 2011, Royston and colleagues proposed a particular class of multi-arm multi-stage (MAMS) designs intended to speed up the evaluation of new treatments in phase II and III clinical trials. Their design, w...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3840569/ https://ncbi.nlm.nih.gov/pubmed/24229079 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2288-13-139 |
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