Survival analysis: coping with non proportional hazards in randomized trials

nork Royston, Patrick, Parmar, Mahesh KB
Argitaratua 2011

Restricted mean survival time: an alternative to the hazard ratio for the design and analysis of randomized trials with a time-to-event outcome

nork Royston, Patrick, Parmar, Mahesh KB
Argitaratua 2013

An approach to trial design and analysis in the era of non-proportional hazards of the treatment effect

nork Royston, Patrick, Parmar, Mahesh KB
Argitaratua 2014

The need for a cultural shift from two-arm to multi-arm RCTS

nork Sydes, Matthew R, Parmar, Mahesh KB
Argitaratua 2013

Augmenting the logrank test in the design of clinical trials in which non-proportional hazards of the treatment effect may be anticipated

nork Royston, Patrick, Parmar, Mahesh K.B.
Argitaratua izan da BMC Med Res Methodol (2016)

A new measure of predictive ability for survival models

nork Choodari-Oskooei, Babak, Royston, Patrick, Parmar, Mahesh KB
Argitaratua 2011

Discrimination-based sample size calculations for multivariable prognostic models for time-to-event data

nork Jinks, Rachel C., Royston, Patrick, Parmar, Mahesh KB
Argitaratua izan da BMC Med Res Methodol (2015)

Assessing the impact of efficacy stopping rules on the error rates under the multi-arm multi-stage framework

nork Blenkinsop, Alexandra, Parmar, Mahesh KB, Choodari-Oskooei, Babak
Argitaratua izan da Clin Trials (2019)

A multi-arm multi-stage clinical trial design for binary outcomes with application to tuberculosis

nork Bratton, Daniel J, Phillips, Patrick PJ, Parmar, Mahesh KB
Argitaratua 2013

The extension of total gain (TG) statistic in survival models: properties and applications

nork Choodari-Oskooei, Babak, Royston, Patrick, Parmar, Mahesh K.B.
Argitaratua izan da BMC Med Res Methodol (2015)

Impact of lack-of-benefit stopping rules on treatment effect estimates of two-arm multi-stage (TAMS) trials with time to event outcome

nork Choodari-Oskooei, Babak, Parmar, Mahesh KB, Royston, Patrick, Bowden, Jack
Argitaratua 2013

Is It Possible to Conduct a Multi-Arm Multi-Stage Platform Trial in Parkinson’s Disease: Lessons Learned from Other Neurodegenerative Disorders and Cancer

nork Zeissler, Marie-Louise, Li, Vivien, Parmar, Mahesh K.B., Carroll, Camille Buchholz
Argitaratua izan da J Parkinsons Dis (2020)

Designs for clinical trials with time-to-event outcomes based on stopping guidelines for lack of benefit

nork Royston, Patrick, Barthel, Friederike M-S, Parmar, Mahesh KB, Choodari-Oskooei, Babak, Isham, Valerie
Argitaratua 2011

The DURATIONS randomised trial design: Estimation targets, analysis methods and operating characteristics

nork Quartagno, Matteo, Carpenter, James R, Walker, A Sarah, Clements, Michelle, Parmar, Mahesh KB
Argitaratua izan da Clin Trials (2020)

Adjuvant therapy with oral sodium clodronate in locally advanced and metastatic prostate cancer: long-term overall survival results from the MRC PR04 and PR05 randomised controlled...

nork Dearnaley, David P, Mason, Malcolm D, Parmar, Mahesh KB, Sanders, Karen, Sydes, Matthew R
Argitaratua 2009

Rethinking non-inferiority: a practical trial design for optimising treatment duration

nork Quartagno, Matteo, Walker, A Sarah, Carpenter, James R, Phillips, Patrick PJ, Parmar, Mahesh KB
Argitaratua izan da Clin Trials (2018)

When should factorial designs be used for late-phase randomised controlled trials?

nork White, Ian R, Szubert, Alexander J, Choodari-Oskooei, Babak, Walker, A Sarah, Parmar, Mahesh KB
Argitaratua izan da Clin Trials (2023)

Sharing data from clinical trials: the rationale for a controlled access approach

nork Sydes, Matthew R, Johnson, Anthony L, Meredith, Sarah K, Rauchenberger, Mary, South, Annabelle, Parmar, Mahesh KB
Argitaratua izan da Trials (2015)

Adding new experimental arms to randomised clinical trials: Impact on error rates

nork Choodari-Oskooei, Babak, Bratton, Daniel J, Gannon, Melissa R, Meade, Angela M, Sydes, Matthew R, Parmar, Mahesh KB
Argitaratua izan da Clin Trials (2020)

Postoperative radiotherapy for non‐small cell lung cancer

nork Burdett, Sarah, Rydzewska, Larysa, Tierney, Jayne, Fisher, David, Parmar, Mahesh KB, Arriagada, Rodrigo, Pignon, Jean Pierre, Le Pechoux, Cecile
Argitaratua izan da Cochrane Database Syst Rev (2016)