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Designs for clinical trials with time-to-event outcomes based on stopping guidelines for lack of benefit
BACKGROUND: The pace of novel medical treatments and approaches to therapy has accelerated in recent years. Unfortunately, many potential therapeutic advances do not fulfil their promise when subjected to randomized controlled trials. It is therefore highly desirable to speed up the process of evalu...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3078872/ https://ncbi.nlm.nih.gov/pubmed/21418571 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1745-6215-12-81 |
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