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Designs for clinical trials with time-to-event outcomes based on stopping guidelines for lack of benefit

BACKGROUND: The pace of novel medical treatments and approaches to therapy has accelerated in recent years. Unfortunately, many potential therapeutic advances do not fulfil their promise when subjected to randomized controlled trials. It is therefore highly desirable to speed up the process of evalu...

詳細記述

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書誌詳細
主要な著者: Royston, Patrick, Barthel, Friederike M-S, Parmar, Mahesh KB, Choodari-Oskooei, Babak, Isham, Valerie
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3078872/
https://ncbi.nlm.nih.gov/pubmed/21418571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1745-6215-12-81
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