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Designs for clinical trials with time-to-event outcomes based on stopping guidelines for lack of benefit

BACKGROUND: The pace of novel medical treatments and approaches to therapy has accelerated in recent years. Unfortunately, many potential therapeutic advances do not fulfil their promise when subjected to randomized controlled trials. It is therefore highly desirable to speed up the process of evalu...

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Detaylı Bibliyografya
Asıl Yazarlar: Royston, Patrick, Barthel, Friederike M-S, Parmar, Mahesh KB, Choodari-Oskooei, Babak, Isham, Valerie
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2011
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3078872/
https://ncbi.nlm.nih.gov/pubmed/21418571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1745-6215-12-81
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