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Adjuvant therapy with oral sodium clodronate in locally advanced and metastatic prostate cancer: long-term overall survival results from the MRC PR04 and PR05 randomised controlled trials

BACKGROUND: Bisphosphonates might modulate the development of symptomatic bone metastases in men with prostate cancer. The Medical Research Council (MRC) PR05 and PR04 randomised controlled trials assessed the use of sodium clodronate, an oral, first-generation bisphosphonate. We report the final an...

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Bibliografiske detaljer
Main Authors: Dearnaley, David P, Mason, Malcolm D, Parmar, Mahesh KB, Sanders, Karen, Sydes, Matthew R
Format: Artigo
Sprog:Inglês
Udgivet: Lancet Pub. Group 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2748902/
https://ncbi.nlm.nih.gov/pubmed/19674936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1470-2045(09)70201-3
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