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Rethinking non-inferiority: a practical trial design for optimising treatment duration
BACKGROUND: Trials to identify the minimal effective treatment duration are needed in different therapeutic areas, including bacterial infections, tuberculosis and hepatitis C. However, standard non-inferiority designs have several limitations, including arbitrariness of non-inferiority margins, cho...
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| Publicado no: | Clin Trials |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
SAGE Publications
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6136078/ https://ncbi.nlm.nih.gov/pubmed/29871495 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1740774518778027 |
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