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Optimising trial designs to identify appropriate antibiotic treatment durations

BACKGROUND: For many infectious conditions, the optimal antibiotic course length remains unclear. The estimation of course length must consider the important trade-off between maximising short- and long-term efficacy and minimising antibiotic resistance and toxicity. MAIN BODY: Evidence on optimal t...

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Dades bibliogràfiques
Publicat a:BMC Med
Autors principals: Pouwels, Koen B., Yin, Mo, Butler, Christopher C., Cooper, Ben S., Wordsworth, Sarah, Walker, A. Sarah, Robotham, Julie V.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6587258/
https://ncbi.nlm.nih.gov/pubmed/31221165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12916-019-1348-z
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