Optimising trial designs to identify appropriate antibiotic treatment durations

BACKGROUND: For many infectious conditions, the optimal antibiotic course length remains unclear. The estimation of course length must consider the important trade-off between maximising short- and long-term efficacy and minimising antibiotic resistance and toxicity. MAIN BODY: Evidence on optimal t...

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Detalles Bibliográficos
Publicado en:BMC Med
Main Authors: Pouwels, Koen B., Yin, Mo, Butler, Christopher C., Cooper, Ben S., Wordsworth, Sarah, Walker, A. Sarah, Robotham, Julie V.
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2019
Assuntos:
Opinion
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6587258/
https://ncbi.nlm.nih.gov/pubmed/31221165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12916-019-1348-z
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