Pcaf Modulates Polyglutamine Pathology in a Drosophila Model of Huntington's Disease

Por Bodai, Laszlo, Pallos, Judit, Thompson, Leslie Michels, Marsh, J. Lawrence
Publicado em 2012

Inhibition of specific HDACs and sirtuins suppresses pathogenesis in a Drosophila model of Huntington’s disease

Por Pallos, Judit, Bodai, Laszlo, Lukacsovich, Tamas, Purcell, Judith M., Steffan, Joan S., Thompson, Leslie Michels, Marsh, J. Lawrence
Publicado em 2008

Identification of combinatorial drug regimens for treatment of Huntington's disease using Drosophila

Por Agrawal, Namita, Pallos, Judit, Slepko, Natalia, Apostol, Barbara L., Bodai, Laszlo, Chang, Ling-Wen, Chiang, Ann-Shyn, Thompson, Leslie Michels, Marsh, J. Lawrence
Publicado em 2005

A cell-based assay for aggregation inhibitors as therapeutics of polyglutamine-repeat disease and validation in Drosophila

Por Apostol, Barbara L., Kazantsev, Alexsey, Raffioni, Simona, Illes, Katalin, Pallos, Judit, Bodai, Laszlo, Slepko, Natalia, Bear, James E., Gertler, Frank B., Hersch, Steven, Housman, David E., Marsh, J. Lawrence, Thompson, Leslie Michels
Publicado em 2003

SIRT2 inhibition achieves neuroprotection by decreasing sterol biosynthesis

Por Luthi-Carter, Ruth, Taylor, David M., Pallos, Judit, Lambert, Emmanuel, Amore, Allison, Parker, Alex, Moffitt, Hilary, Smith, Donna L., Runne, Heike, Gokce, Ozgun, Kuhn, Alexandre, Xiang, Zhongmin, Maxwell, Michele M., Reeves, Steven A., Bates, Gillian P., Neri, Christian, Thompson, Leslie M., Marsh, J. Lawrence, Kazantsev, Aleksey G.
Publicado em 2010

Histone deacetylase (HDAC) inhibitors targeting HDAC3 and HDAC1 ameliorate polyglutamine-elicited phenotypes in model systems of Huntington's disease

Por Jia, Haiqun, Pallos, Judit, Jacques, Vincent, Lau, Alice, Tang, Bin, Cooper, Andrew, Syed, Adeela, Purcell, Judith, Chen, Yi, Sharma, Shefali, Sangrey, Gavin R., Darnell, Shayna B., Plasterer, Heather, Sadri-Vakili, Ghazaleh, Gottesfeld, Joel M., Thompson, Leslie M., Rusche, James R., Marsh, J. Lawrence, Thomas, Elizabeth A.
Publicado em 2012

SUMO-2 and PIAS1 Modulate Insoluble Mutant Huntingtin Protein Accumulation

Por O’Rourke, Jacqueline Gire, Gareau, Jaclyn R., Ochaba, Joseph, Song, Wan, Raskó, Tamás, Reverter, David, Lee, John, Monteys, Alex Mas, Pallos, Judit, Mee, Lisa, Vashishtha, Malini, Apostol, Barbara L., Nicholson, Thomas Peter, Illes, Katalin, Zhu, Ya-Zhen, Dasso, Mary, Bates, Gillian P., Difiglia, Marian, Davidson, Beverly, Wanker, Erich E., Marsh, J. Lawrence, Lima, Christopher D., Steffan, Joan S., Thompson, Leslie M.
Publicado em 2013

Inhibition of transglutaminase 2 mitigates transcriptional dysregulation in models of Huntington disease

Por McConoughey, Stephen J, Basso, Manuela, Niatsetskaya, Zoya V, Sleiman, Sama F, Smirnova, Natalia A, Langley, Brett C, Mahishi, Lata, Cooper, Arthur J L, Antonyak, Marc A, Cerione, Rick A, Li, Bo, Starkov, Anatoly, Chaturvedi, Rajnish Kumar, Beal, M Flint, Coppola, Giovanni, Geschwind, Daniel H, Ryu, Hoon, Xia, Li, Iismaa, Siiri E, Pallos, Judit, Pasternack, Ralf, Hils, Martin, Fan, Jing, Raymond, Lynn A, Marsh, J Lawrence, Thompson, Leslie M, Ratan, Rajiv R
Publicado em 2010