Searching for Disease Modifiers - PKC Activation and HDAC Inhibition - A Dual Drug Approach to Alzheimer's Disease that Reduces Aβ Production while Blocking Oxidative Stress

Por Kozikowski, Alan P., Chen, Yihua, Subhasish, Tapadar, Lewin, Nancy E., Blumberg, Peter M., Zhong, Zhenyu, D'Annibale, Melissa A., Wang, Weng-Long, Shen, Yong, Langley, Brett C.
Publicado em 2009

Mithramycin Is a Gene-Selective Sp1 Inhibitor That Identifies a Biological Intersection between Cancer and Neurodegeneration

Por Sleiman, Sama F., Langley, Brett C., Basso, Manuela, Berlin, Jill, Xia, Li, Payappilly, Jimmy B., Kharel, Madan K., Guo, Hengchang, Marsh, J. Lawrence, Thompson, Leslie Michels, Mahishi, Lata, Ahuja, Preeti, MacLellan, W. Robb, Geschwind, Daniel H., Coppola, Giovanni, Rohr, Jürgen, Ratan, Rajiv R.
Publicado em 2011

Inhibition of transglutaminase 2 mitigates transcriptional dysregulation in models of Huntington disease

Por McConoughey, Stephen J, Basso, Manuela, Niatsetskaya, Zoya V, Sleiman, Sama F, Smirnova, Natalia A, Langley, Brett C, Mahishi, Lata, Cooper, Arthur J L, Antonyak, Marc A, Cerione, Rick A, Li, Bo, Starkov, Anatoly, Chaturvedi, Rajnish Kumar, Beal, M Flint, Coppola, Giovanni, Geschwind, Daniel H, Ryu, Hoon, Xia, Li, Iismaa, Siiri E, Pallos, Judit, Pasternack, Ralf, Hils, Martin, Fan, Jing, Raymond, Lynn A, Marsh, J Lawrence, Thompson, Leslie M, Ratan, Rajiv R
Publicado em 2010