Curtailing side effects in chemotherapy: a tale of PKCδ in cisplatin treatment

por Pabla, Navjotsingh, Dong, Zheng
Publicado 2012

CCR 20(th) Anniversary Commentary: BMS-247550—Microtubule Stabilization as Successful Targeted Therapy

por Pabla, Navjotsingh, Sparreboom, Alex
Publicado en Clin Cancer Res (2015)

Checkpoint kinase 1 (Chk1)-short is a splice variant and endogenous inhibitor of Chk1 that regulates cell cycle and DNA damage checkpoints

por Pabla, Navjotsingh, Bhatt, Kirti, Dong, Zheng
Publicado 2012

Checkpoint kinase 1 in DNA damage response and cell cycle regulation

por Patil, Mallikarjun, Pabla, Navjotsingh, Dong, Zheng
Publicado 2013

Nek1 phosphorylates Von Hippel-Lindau tumor suppressor to promote its proteasomal degradation and ciliary destabilization

por Patil, Mallikarjun, Pabla, Navjotsingh, Huang, Shuang, Dong, Zheng
Publicado 2013

The copper transporter Ctr1 contributes to cisplatin uptake by renal tubular cells during cisplatin nephrotoxicity

por Pabla, Navjotsingh, Murphy, Robert F., Liu, Kebin, Dong, Zheng
Publicado 2009

Nek1 interacts with Ku80 to assist chromatin loading of replication factors and S-phase progression

por Patil, Mallikarjun, Pabla, Navjotsingh, Ding, Han-Fei, Dong, Zheng
Publicado 2013

DNA Damage Response in Cisplatin-Induced Nephrotoxicity

por Zhu, Shiyao, Pabla, Navjotsingh, Tang, Chengyuan, He, Liyu, Dong, Zheng
Publicado en Arch Toxicol (2015)

ATR-Chk2 signaling in p53 activation and DNA damage response during cisplatin-induced apoptosis. VOLUME 283 (2008) PAGES 6572-6583

por Pabla, Navjotsingh, Huang, Shuang, Mi, Qing-Sheng, Daniel, Rene, Dong, Zheng
Publicado 2008

hMSH2 Recruits ATR to DNA Damage Sites for Activation during DNA Damage-induced Apoptosis

por Pabla, Navjotsingh, Ma, Zhengwei, McIlhatton, Michael A., Fishel, Richard, Dong, Zheng
Publicado 2011

PKC-δ Promotes Renal Tubular Cell Apoptosis Associated with Proteinuria

por Li, Xiaoning, Pabla, Navjotsingh, Wei, Qingqing, Dong, Guie, Messing, Robert O., Wang, Cong-Yi, Dong, Zheng
Publicado 2010

Inhibition of PKCδ reduces cisplatin-induced nephrotoxicity without blocking chemotherapeutic efficacy in mouse models of cancer

por Pabla, Navjotsingh, Dong, Guie, Jiang, Man, Huang, Shuang, Kumar, M. Vijay, Messing, Robert O., Dong, Zheng
Publicado 2011

MicroRNA-687 Induced by Hypoxia-Inducible Factor-1 Targets Phosphatase and Tensin Homolog in Renal Ischemia-Reperfusion Injury

por Bhatt, Kirti, Wei, Qingqing, Pabla, Navjotsingh, Dong, Guie, Mi, Qing-Sheng, Liang, Mingyu, Mei, Changlin, Dong, Zheng
Publicado en J Am Soc Nephrol (2015)

Cisplatin-Induced Renal Injury is Independently Mediated by OCT2 and p53

por Sprowl, Sprowl, Lancaster, Cynthia S., Pabla, Navjotsingh, Hermann, Edwin, Kosloske, Ashley M., Gibson, Alice A., Li, Lie, Zeeh, Dorothea, Schlatter, Eberhard, Janke, Laura J., Ciarimboli, Giuliano, Sparreboom, Alex
Publicado 2014

Mitigation of acute kidney injury by cell-cycle inhibitors that suppress both CDK4/6 and OCT2 functions

por Pabla, Navjotsingh, Gibson, Alice A., Buege, Mike, Ong, Su Sien, Li, Lie, Hu, Shuiying, Du, Guoqing, Sprowl, Jason A., Vasilyeva, Aksana, Janke, Laura J., Schlatter, Eberhard, Chen, Taosheng, Ciarimboli, Giuliano, Sparreboom, Alex
Publicado en Proc Natl Acad Sci U S A (2015)

OCTN1 is a high-affinity carrier of nucleoside analogs

por Drenberg, Christina D., Gibson, Alice A., Pounds, Stanley B., Shi, Lei, Rhinehart, Dena P., Li, Lie, Hu, Shuiying, Du, Guoqing, Nies, Anne T., Schwab, Matthias, Pabla, Navjotsingh, Blum, William, Gruber, Tanja A., Baker, Sharyn D., Sparreboom, Alex
Publicado en Cancer Res (2017)

Hypoxia-induced upregulation of BMX kinase mediates therapeutic resistance in acute myeloid leukemia

por van Oosterwijk, Jolieke G., Buelow, Daelynn R., Drenberg, Christina D., Vasilyeva, Aksana, Li, Lie, Shi, Lei, Wang, Yong-Dong, Finkelstein, David, Shurtleff, Sheila A., Janke, Laura J., Pounds, Stanley, Rubnitz, Jeffrey E., Inaba, Hiroto, Pabla, Navjotsingh, Baker, Sharyn D.
Publicado en J Clin Invest (2017)

A phosphotyrosine switch regulates organic cation transporters

por Sprowl, Jason A., Ong, Su Sien, Gibson, Alice A., Hu, Shuiying, Du, Guoqing, Lin, Wenwei, Li, Lie, Bharill, Shashank, Ness, Rachel A., Stecula, Adrian, Offer, Steven M., Diasio, Robert B., Nies, Anne T., Schwab, Matthias, Cavaletti, Guido, Schlatter, Eberhard, Ciarimboli, Giuliano, Schellens, Jan H. M., Isacoff, Ehud Y., Sali, Andrej, Chen, Taosheng, Baker, Sharyn D., Sparreboom, Alex, Pabla, Navjotsingh
Publicado en Nat Commun (2016)