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Checkpoint kinase 1 in DNA damage response and cell cycle regulation
Originally identified as a mediator of DNA damage response (DDR), checkpoint kinase 1 (Chk1) has a broader role in checkpoint activation in DDR and normal cell cycle regulation. Chk1 activation involves phosphorylation at conserved sites. However, recent work has identified a splice variant of Chk1,...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3731415/ https://ncbi.nlm.nih.gov/pubmed/23508805 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-013-1307-3 |
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