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DNA Damage Response in Cisplatin-Induced Nephrotoxicity

Cisplatin and its derivatives are widely used chemotherapeutic drugs for cancer treatment. However, they have debilitating side-effects in normal tissues and induce ototoxicity, neurotoxicity, and nephrotoxicity. In kidneys, cisplatin preferentially accumulates in renal tubular cells causing tubular...

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Detalhes bibliográficos
Publicado no:Arch Toxicol
Main Authors: Zhu, Shiyao, Pabla, Navjotsingh, Tang, Chengyuan, He, Liyu, Dong, Zheng
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4734632/
https://ncbi.nlm.nih.gov/pubmed/26564230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-015-1633-3
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