DNA Damage Response in Cisplatin-Induced Nephrotoxicity

Cisplatin and its derivatives are widely used chemotherapeutic drugs for cancer treatment. However, they have debilitating side-effects in normal tissues and induce ototoxicity, neurotoxicity, and nephrotoxicity. In kidneys, cisplatin preferentially accumulates in renal tubular cells causing tubular...

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Bibliographic Details
Published in:Arch Toxicol
Main Authors: Zhu, Shiyao, Pabla, Navjotsingh, Tang, Chengyuan, He, Liyu, Dong, Zheng
Format: Artigo
Language:Inglês
Published: 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4734632/
https://ncbi.nlm.nih.gov/pubmed/26564230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-015-1633-3
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