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DNA Damage Response in Cisplatin-Induced Nephrotoxicity
Cisplatin and its derivatives are widely used chemotherapeutic drugs for cancer treatment. However, they have debilitating side-effects in normal tissues and induce ototoxicity, neurotoxicity, and nephrotoxicity. In kidneys, cisplatin preferentially accumulates in renal tubular cells causing tubular...
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| 發表在: | Arch Toxicol |
|---|---|
| Main Authors: | , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4734632/ https://ncbi.nlm.nih.gov/pubmed/26564230 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-015-1633-3 |
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