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hMSH2 Recruits ATR to DNA Damage Sites for Activation during DNA Damage-induced Apoptosis
DNA damage response (DDR) activates a complex signaling network that triggers DNA repair, cell cycle arrest, and/or cell death. Depending on the type and severity of DNA lesion, DDR is controlled by “master” regulators including ATM and ATR protein kinases. Cisplatin, a major chemotherapy drug that...
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| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Biochemistry and Molecular Biology
2011
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3060494/ https://ncbi.nlm.nih.gov/pubmed/21285353 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.210989 |
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