Human MSH2 (hMSH2) Protein Controls ATP Processing by hMSH2-hMSH6

The mechanics of hMSH2-hMSH6 ATP binding and hydrolysis are critical to several proposed mechanisms for mismatch repair (MMR), which in turn rely on the detailed coordination of ATP processing between the individual hMSH2 and hMSH6 subunits. Here we show that hMSH2-hMSH6 is strictly controlled by hM...

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Autores principales: Heinen, Christopher D., Cyr, Jennifer L., Cook, Christopher, Punja, Nidhi, Sakato, Miho, Forties, Robert A., Lopez, Juana Martin, Hingorani, Manju M., Fishel, Richard
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2011
Materias:
DNA and Chromosomes
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3220577/
https://ncbi.nlm.nih.gov/pubmed/21937421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.297523
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