Human MSH2 (hMSH2) Protein Controls ATP Processing by hMSH2-hMSH6

The mechanics of hMSH2-hMSH6 ATP binding and hydrolysis are critical to several proposed mechanisms for mismatch repair (MMR), which in turn rely on the detailed coordination of ATP processing between the individual hMSH2 and hMSH6 subunits. Here we show that hMSH2-hMSH6 is strictly controlled by hM...

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Detalhes bibliográficos
Main Authors: Heinen, Christopher D., Cyr, Jennifer L., Cook, Christopher, Punja, Nidhi, Sakato, Miho, Forties, Robert A., Lopez, Juana Martin, Hingorani, Manju M., Fishel, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
DNA and Chromosomes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3220577/
https://ncbi.nlm.nih.gov/pubmed/21937421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.297523
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