Genetic Biomarkers in Epilepsy

por Weber, Yvonne G., Nies, Anne T., Schwab, Matthias, Lerche, Holger
Publicado 2014

Proton Pump Inhibitors Inhibit Metformin Uptake by Organic Cation Transporters (OCTs)

por Nies, Anne T., Hofmann, Ute, Resch, Claudia, Schaeffeler, Elke, Rius, Maria, Schwab, Matthias
Publicado 2011

Interaction of Remdesivir with Clinically Relevant Hepatic Drug Uptake Transporters

por Nies, Anne T., König, Jörg, Hofmann, Ute, Kölz, Charlotte, Fromm, Martin F., Schwab, Matthias
Publicado en Pharmaceutics (2021)

The Membrane Transporter OAT7 (SLC22A9) Is Not a Susceptibility Factor for Osteoporosis in Europeans

por Nies, Anne T., Weiss, Stefan, Schaeffeler, Elke, Hannemann, Anke, Völker, Uwe, Wallaschofski, Henri, Schwab, Matthias
Publicado en Front Endocrinol (Lausanne) (2020)

Genetics is a major determinant of expression of the human hepatic uptake transporter OATP1B1, but not of OATP1B3 and OATP2B1

por Nies, Anne T, Niemi, Mikko, Burk, Oliver, Winter, Stefan, Zanger, Ulrich M, Stieger, Bruno, Schwab, Matthias, Schaeffeler, Elke
Publicado 2013

Development of Human Membrane Transporters: Drug Disposition and Pharmacogenetics

por Mooij, Miriam G., Nies, Anne T., Knibbe, Catherijne A. J., Schaeffeler, Elke, Tibboel, Dick, Schwab, Matthias, de Wildt, Saskia N.
Publicado en Clin Pharmacokinet (2015)

DNA methylation is associated with downregulation of the organic cation transporter OCT1 (SLC22A1) in human hepatocellular carcinoma

por Schaeffeler, Elke, Hellerbrand, Claus, Nies, Anne T, Winter, Stefan, Kruck, Stephan, Hofmann, Ute, van der Kuip, Heiko, Zanger, Ulrich M, Koepsell, Hermann, Schwab, Matthias
Publicado 2011

Sorafenib activity and disposition in liver cancer does not depend on organic cation transporter 1 (OCT1)

por Chen, Mingqing, Neul, Claudia, Schaeffeler, Elke, Frisch, Franziska, Winter, Stefan, Schwab, Matthias, Koepsell, Hermann, Hu, Shuiying, Laufer, Stefan, Baker, Sharyn D., Sparreboom, Alex, Nies, Anne T.
Publicado en Clin Pharmacol Ther (2019)

MCT4 surpasses the prognostic relevance of the ancillary protein CD147 in clear cell renal cell carcinoma

por Fisel, Pascale, Stühler, Viktoria, Bedke, Jens, Winter, Stefan, Rausch, Steffen, Hennenlotter, Jörg, Nies, Anne T., Stenzl, Arnulf, Scharpf, Marcus, Fend, Falko, Kruck, Stephan, Schwab, Matthias, Schaeffeler, Elke
Publicado en Oncotarget (2015)

Effects of a Common Eight Base Pairs Duplication at the Exon 7-Intron 7 Junction on Splicing, Expression, and Function of OCT1

por Römer, Sarah, Meyer, Marleen J., Klein, Kathrin, Schneider, Lennart V., Matthaei, Johannes, Tzvetkova, Ana, Łapczuk-Romańska, Joanna, Gaedcke, Jochen, Droździk, Marek, Brockmöller, Jürgen, Nies, Anne T., Tzvetkov, Mladen V.
Publicado en Front Pharmacol (2021)

Cellular uptake of imatinib into leukemic cells is independent of human organic cation transporter 1 (OCT1)

por Nies, Anne T., Schaeffeler, Elke, van der Kuip, Heiko, Cascorbi, Ingolf, Bruhn, Oliver, Kneba, Michael, Pott, Christiane, Hofmann, Ute, Volk, Christopher, Hu, Shuiying, Baker, Sharyn D., Sparreboom, Alex, Ruth, Peter, Koepsell, Hermann, Schwab, Matthias
Publicado 2013

OCTN1 is a high-affinity carrier of nucleoside analogs

por Drenberg, Christina D., Gibson, Alice A., Pounds, Stanley B., Shi, Lei, Rhinehart, Dena P., Li, Lie, Hu, Shuiying, Du, Guoqing, Nies, Anne T., Schwab, Matthias, Pabla, Navjotsingh, Blum, William, Gruber, Tanja A., Baker, Sharyn D., Sparreboom, Alex
Publicado en Cancer Res (2017)

Methylomes of renal cell lines and tumors or metastases differ significantly with impact on pharmacogenes

por Winter, Stefan, Fisel, Pascale, Büttner, Florian, Rausch, Steffen, D’Amico, Debora, Hennenlotter, Jörg, Kruck, Stephan, Nies, Anne T., Stenzl, Arnulf, Junker, Kerstin, Scharpf, Marcus, Hofmann, Ute, van der Kuip, Heiko, Fend, Falko, Ott, German, Agaimy, Abbas, Hartmann, Arndt, Bedke, Jens, Schwab, Matthias, Schaeffeler, Elke
Publicado en Sci Rep (2016)

A phosphotyrosine switch regulates organic cation transporters

por Sprowl, Jason A., Ong, Su Sien, Gibson, Alice A., Hu, Shuiying, Du, Guoqing, Lin, Wenwei, Li, Lie, Bharill, Shashank, Ness, Rachel A., Stecula, Adrian, Offer, Steven M., Diasio, Robert B., Nies, Anne T., Schwab, Matthias, Cavaletti, Guido, Schlatter, Eberhard, Ciarimboli, Giuliano, Schellens, Jan H. M., Isacoff, Ehud Y., Sali, Andrej, Chen, Taosheng, Baker, Sharyn D., Sparreboom, Alex, Pabla, Navjotsingh
Publicado en Nat Commun (2016)

Targeting OCT3 attenuates doxorubicin-induced cardiac injury

por Huang, Kevin M., Zavorka Thomas, Megan, Magdy, Tarek, Eisenmann, Eric D., Uddin, Muhammad Erfan, DiGiacomo, Duncan F., Pan, Alexander, Keiser, Markus, Otter, Marcus, Xia, Sherry H., Li, Yang, Jin, Yan, Fu, Qiang, Gibson, Alice A., Bonilla, Ingrid M., Carnes, Cynthia A., Corps, Kara N., Coppola, Vincenzo, Smith, Sakima A., Addison, Daniel, Nies, Anne T., Bundschuh, Ralf, Chen, Taosheng, Lustberg, Maryam B., Wang, Joanne, Oswald, Stefan, Campbell, Moray J., Yan, Pearlly S., Baker, Sharyn D., Hu, Shuiying, Burridge, Paul W., Sparreboom, Alex
Publicado en Proc Natl Acad Sci U S A (2021)