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Sorafenib activity and disposition in liver cancer does not depend on organic cation transporter 1 (OCT1)
Systemic therapy of advanced hepatocellular carcinoma (HCC) with the small molecule multi-kinase inhibitor sorafenib is associated with large inter-individual pharmacokinetic variability and unpredictable side effects potentially requiring dose reduction or treatment termination. Organic cation tran...
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| Publicado no: | Clin Pharmacol Ther |
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| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6925656/ https://ncbi.nlm.nih.gov/pubmed/31350763 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpt.1588 |
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