DNA methylation is associated with downregulation of the organic cation transporter OCT1 (SLC22A1) in human hepatocellular carcinoma

BACKGROUND: Organic cation transporters (OCTs) determine not only physiological processes but are also involved in the cellular uptake of anticancer agents. Based on microarray analyses in hepatocellular carcinoma (HCC), SLC22A1/OCT1 mRNA seems to be downregulated, but systematic protein expression...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Schaeffeler, Elke, Hellerbrand, Claus, Nies, Anne T, Winter, Stefan, Kruck, Stephan, Hofmann, Ute, van der Kuip, Heiko, Zanger, Ulrich M, Koepsell, Hermann, Schwab, Matthias
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2011
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3334547/
https://ncbi.nlm.nih.gov/pubmed/22196450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gm298
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky