DNA methylation is associated with downregulation of the organic cation transporter OCT1 (SLC22A1) in human hepatocellular carcinoma

BACKGROUND: Organic cation transporters (OCTs) determine not only physiological processes but are also involved in the cellular uptake of anticancer agents. Based on microarray analyses in hepatocellular carcinoma (HCC), SLC22A1/OCT1 mRNA seems to be downregulated, but systematic protein expression...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Schaeffeler, Elke, Hellerbrand, Claus, Nies, Anne T, Winter, Stefan, Kruck, Stephan, Hofmann, Ute, van der Kuip, Heiko, Zanger, Ulrich M, Koepsell, Hermann, Schwab, Matthias
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3334547/
https://ncbi.nlm.nih.gov/pubmed/22196450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gm298
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares