Downregulation of organic cation transporters OCT1 (SLC22A1) and OCT3 (SLC22A3) in human hepatocellular carcinoma and their prognostic significance

BACKGROUND: Organic cation transporters (OCT) are responsible for the uptake and intracellular inactivation of a broad spectrum of endogenous substrates and detoxification of xenobiotics and chemotherapeutics. The transporters became pharmaceutically interesting, because OCTs are determinants of the...

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Autori principali: Heise, Michael, Lautem, Anja, Knapstein, Johanna, Schattenberg, Jörn M, Hoppe-Lotichius, Maria, Foltys, Daniel, Weiler, Nina, Zimmermann, Anca, Schad, Arno, Gründemann, Dirk, Otto, Gerd, Galle, Peter R, Schuchmann, Marcus, Zimmermann, Tim
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2012
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3323414/
https://ncbi.nlm.nih.gov/pubmed/22439694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-12-109
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