Loss of organic cation transporter 3 (Oct3) leads to enhanced proliferation and hepatocarcinogenesis

BACKGROUND: Organic cation transporters (OCT) are responsible for the uptake of a broad spectrum of endogenous and exogenous substrates. Downregulation of OCT is frequently observed in human hepatocellular carcinoma (HCC) and is associated with a poor outcome. The aim of our current study was to elu...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Vollmar, Johanna, Lautem, Anja, Closs, Ellen, Schuppan, Detlef, Kim, Yong Ook, Grimm, Daniel, Marquardt, Jens U., Fuchs, Peter, Straub, Beate K., Schad, Arno, Gründemann, Dirk, Schattenberg, Jörn M., Gehrke, Nadine, Wörns, Marcus A., Baumgart, Jan, Galle, Peter R., Zimmermann, Tim
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5777802/
https://ncbi.nlm.nih.gov/pubmed/29383190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.23372
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