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Functional inhibition of Oct leads to HNF4α upregulation

Organic cation transporters (human, OCT; mouse, Oct) are responsible for the intracellular uptake and detoxification of a broad spectrum of endogenous and exogenous substrates. The OCT1 gene SLC22A1 (human; mouse, Scl22a1) is transactivated by hepatocyte nuclear factor 4α (human, HNF4α; mouse, Hnf4α...

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Dades bibliogràfiques
Publicat a:Exp Ther Med
Autors principals: Vollmar, Johanna, Kim, Yong Ook, Marquardt, Jens Uwe, Galle, Peter R., Schuppan, Detlef, Zimmermann, Tim
Format: Artigo
Idioma:Inglês
Publicat: D.A. Spandidos 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7903485/
https://ncbi.nlm.nih.gov/pubmed/33732322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2021.9780
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