Oct4 and Hnf4α-induced hepatic stem cells ameliorate chronic liver injury in liver fibrosis model

Direct conversion from fibroblasts to generate hepatocyte like-cells (iHeps) bypassing the pluripotent state has been described in previous reports as an attractive method acquiring hepatocytes for cell-based therapy. The limited proliferation of iHeps, however, has hampered it uses in cell-based th...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Park, Myung Rae, Wong, Man Sze, Araúzo-Bravo, Marcos J., Lee, Hyunah, Nam, Donggyu, Park, Soo Yong, Seo, Hong Dae, Lee, Sang Min, Zeilhofer, Hans Florian, Zaehres, Holm, Schöler, Hans R., Kim, Jeong Beom
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2019
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6690533/
https://ncbi.nlm.nih.gov/pubmed/31404112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0221085
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