Counteracting Activities of OCT4 and KLF4 during Reprogramming to Pluripotency

Differentiated cells can be reprogrammed into induced pluripotent stem cells (iPSCs) after overexpressing four transcription factors, of which Oct4 is essential. To elucidate the role of Oct4 during reprogramming, we investigated the immediate transcriptional response to inducible Oct4 overexpressio...

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Detalhes bibliográficos
Main Authors: Tiemann, Ulf, Marthaler, Adele Gabriele, Adachi, Kenjiro, Wu, Guangming, Fischedick, Gerrit Ulf Lennart, Araúzo-Bravo, Marcos Jesús, Schöler, Hans Robert, Tapia, Natalia
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3964287/
https://ncbi.nlm.nih.gov/pubmed/24672757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2014.01.005
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