Dissecting the role of distinct OCT4-SOX2 heterodimer configurations in pluripotency

The transcription factors OCT4 and SOX2 are required for generating induced pluripotent stem cells (iPSCs) and for maintaining embryonic stem cells (ESCs). OCT4 and SOX2 associate and bind to DNA in different configurations depending on the arrangement of their individual DNA binding elements. Here...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Tapia, Natalia, MacCarthy, Caitlin, Esch, Daniel, Gabriele Marthaler, Adele, Tiemann, Ulf, Araúzo-Bravo, Marcos J., Jauch, Ralf, Cojocaru, Vlad, Schöler, Hans R.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2015
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4551974/
https://ncbi.nlm.nih.gov/pubmed/26314899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep13533
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