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Nucleosomal DNA Dynamics Mediate Oct4 Pioneer Factor Binding
Transcription factor (TF) proteins bind to DNA to regulate gene expression. Normally, accessibility to DNA is required for their function. However, in the nucleus, the DNA is often inaccessible, wrapped around histone proteins in nucleosomes forming the chromatin. Pioneer TFs are thought to induce c...
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| Published in: | Biophys J |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
The Biophysical Society
2020
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7202942/ https://ncbi.nlm.nih.gov/pubmed/32027821 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.12.038 |
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