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Nucleosomal DNA Dynamics Mediate Oct4 Pioneer Factor Binding
Transcription factor (TF) proteins bind to DNA to regulate gene expression. Normally, accessibility to DNA is required for their function. However, in the nucleus, the DNA is often inaccessible, wrapped around histone proteins in nucleosomes forming the chromatin. Pioneer TFs are thought to induce c...
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| Publicado no: | Biophys J |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7202942/ https://ncbi.nlm.nih.gov/pubmed/32027821 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.12.038 |
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