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Histone tails cooperate to control the breathing of genomic nucleosomes

Genomic DNA is packaged in chromatin, a dynamic fiber variable in size and compaction. In chromatin, repeating nucleosome units wrap 145–147 DNA basepairs around histone proteins. Genetic and epigenetic regulation of genes relies on structural transitions in chromatin which are driven by intra- and...

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Bibliografiske detaljer
Udgivet i:PLoS Comput Biol
Main Authors: Huertas, Jan, Schöler, Hans Robert, Cojocaru, Vlad
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8174689/
https://ncbi.nlm.nih.gov/pubmed/34081696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1009013
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