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Nucleosomal DNA Dynamics Mediate Oct4 Pioneer Factor Binding

Transcription factor (TF) proteins bind to DNA to regulate gene expression. Normally, accessibility to DNA is required for their function. However, in the nucleus, the DNA is often inaccessible, wrapped around histone proteins in nucleosomes forming the chromatin. Pioneer TFs are thought to induce c...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Biophys J
Egile Nagusiak: Huertas, Jan, MacCarthy, Caitlin M., Schöler, Hans R., Cojocaru, Vlad
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Biophysical Society 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7202942/
https://ncbi.nlm.nih.gov/pubmed/32027821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.12.038
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