Changing POU dimerization preferences converts Oct6 into a pluripotency inducer

The transcription factor Oct4 is a core component of molecular cocktails inducing pluripotent stem cells (iPSCs), while other members of the POU family cannot replace Oct4 with comparable efficiency. Rather, group III POU factors such as Oct6 induce neural lineages. Here, we sought to identify molec...

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Vydáno v:EMBO Rep
Hlavní autoři: Jerabek, Stepan, Ng, Calista KL, Wu, Guangming, Arauzo‐Bravo, Marcos J, Kim, Kee‐Pyo, Esch, Daniel, Malik, Vikas, Chen, Yanpu, Velychko, Sergiy, MacCarthy, Caitlin M, Yang, Xiaoxiao, Cojocaru, Vlad, Schöler, Hans R, Jauch, Ralf
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2016
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Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5286379/
https://ncbi.nlm.nih.gov/pubmed/28007765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201642958
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