Changing POU dimerization preferences converts Oct6 into a pluripotency inducer

The transcription factor Oct4 is a core component of molecular cocktails inducing pluripotent stem cells (iPSCs), while other members of the POU family cannot replace Oct4 with comparable efficiency. Rather, group III POU factors such as Oct6 induce neural lineages. Here, we sought to identify molec...

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Gepubliceerd in:EMBO Rep
Hoofdauteurs: Jerabek, Stepan, Ng, Calista KL, Wu, Guangming, Arauzo‐Bravo, Marcos J, Kim, Kee‐Pyo, Esch, Daniel, Malik, Vikas, Chen, Yanpu, Velychko, Sergiy, MacCarthy, Caitlin M, Yang, Xiaoxiao, Cojocaru, Vlad, Schöler, Hans R, Jauch, Ralf
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2016
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Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5286379/
https://ncbi.nlm.nih.gov/pubmed/28007765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201642958
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