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Reprogramming to Pluripotency through a Somatic Stem Cell Intermediate

Transcription factor-based reprogramming can lead to the successful switching of cell fates. We have recently reported that mouse embryonic fibroblasts (MEFs) can be directly reprogrammed into induced neural stem cells (iNSCs) after the forced expression of Brn4, Sox2, Klf4, and Myc. Here, we tested...

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Bibliografiske detaljer
Main Authors: Marthaler, Adele G., Tiemann, Ulf, Araúzo-Bravo, Marcos J., Wu, Guangming, Zaehres, Holm, Hyun, Jung Keun, Han, Dong Wook, Schöler, Hans R., Tapia, Natalia
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3874029/
https://ncbi.nlm.nih.gov/pubmed/24386457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0085138
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