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Reprogramming to Pluripotency through a Somatic Stem Cell Intermediate

Transcription factor-based reprogramming can lead to the successful switching of cell fates. We have recently reported that mouse embryonic fibroblasts (MEFs) can be directly reprogrammed into induced neural stem cells (iNSCs) after the forced expression of Brn4, Sox2, Klf4, and Myc. Here, we tested...

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Hlavní autoři: Marthaler, Adele G., Tiemann, Ulf, Araúzo-Bravo, Marcos J., Wu, Guangming, Zaehres, Holm, Hyun, Jung Keun, Han, Dong Wook, Schöler, Hans R., Tapia, Natalia
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3874029/
https://ncbi.nlm.nih.gov/pubmed/24386457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0085138
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