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Role of Oct4 in the early embryo development

Oct4 is a key component of the pluripotency regulatory network, and its reciprocal interaction with Cdx2 has been shown to be a determinant of either the self-renewal of embryonic stem cells (ESCs) or their differentiation into trophoblast. Oct4 of maternal origin is postulated to play critical role...

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Pubblicato in:Cell Regen
Autori principali: Wu, Guangming, Schöler, Hans R
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4230828/
https://ncbi.nlm.nih.gov/pubmed/25408886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-9769-3-7
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