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Biological importance of OCT transcription factors in reprogramming and development
Ectopic expression of Oct4, Sox2, Klf4 and c-Myc can reprogram somatic cells into induced pluripotent stem cells (iPSCs). Attempts to identify genes or chemicals that can functionally replace each of these four reprogramming factors have revealed that exogenous Oct4 is not necessary for reprogrammin...
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| Publicado no: | Exp Mol Med |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8257633/ https://ncbi.nlm.nih.gov/pubmed/34117345 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-021-00637-4 |
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